Warshaw’s Pioneering Heart Failure Discovery in 2000 Leads to New Potential Treatment

More than 15 years ago, David Warshaw, Ph.D., and coworkers discovered the precise malfunction of a specific protein in the heart that leads to hypertrophic cardiomyopathy, a common culprit in cases of sudden death in young athletes.

Now, a team of scientists has used some of Warshaw’s earlier findings to develop a possible treatment to prevent hypertrophic cardiomyopathy (HCM), an inherited disease that can cause the heart to thicken and stop pumping blood effectively, leading to heart failure. Warshaw, professor and chair of molecular physiology and biophysics at the University of Vermont (UVM) College of Medicine, wrote about the significance of this potential therapy for a “Perspectives” column in the February 5, 2016 issue of the journal ScienceRead more

Article featured on the COM “Spotlight” news on 02-04-2016.