Wolfgang R. Dostmann, M.D./Ph.D.

Wolfgang R. Dostmann, M.D./Ph.D.

Adjunct Faculty


Please see The Dostmann Lab Website for more information.


330 HSRF

330 HSRF

Current Publications:

Moon TM, Tykocki NR, Sheehe JL, Osborne BW, Tegge W, Brayden JE, Dostmann WR (2015) Synthetic Peptides as cGMP-Independent Activators of cGMP-Dependent Protein Kinase Iα. Chem Biol 22(12): 1653-61.

Arora K, Sinha C, Zhang W, Moon CS, Ren A, Yarlagadda S, Dostmann WR, Adebiyi A, Haberman Y, Denson LA, Wang X, Naren AP (2015) Altered cGMP dynamics at the plasma membrane contribute to diarrhea in ulcerative colitis. Am J Pathol 185(10): 2790-804.

Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DA (2015) Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease. Nature 519(7544): 472-6.

Held KF, Dostmann WR (2013) Real-time monitoring the spatiotemporal dynamics of intracellular cGMP in vascular smooth muscle cells. Methods Mol Biol 1020: 131-45.

Moon TM, Osborne BW, Dostmann WR (2013) The switch helix: a putative combinatorial relay for interprotomer communication in cGMP-dependent protein kinase. Biochim Biophys Acta 1834(7): 1346-51.

Held KF, Dostmann WR (2012) Sub-Nanomolar Sensitivity of Nitric Oxide Mediated Regulation of cGMP and Vasomotor Reactivity in Vascular Smooth Muscle. Front Pharmacol 3: 130.

Miller CL, Cai Y, Oikawa M, Thomas T, Dostmann WR, Zaccolo M, Fujiwara K, Yan C (2011) Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart. Basic Res Cardiol 106(6): 1023-39.


All Dostmann publications

Selected Awards

Venia legendi, (Privatdozent), Munich/Bavaria, Germany 1997