Guy Kennedy

Guy  Kennedy,

Research Engineer


HSRF 115

Lab Group

A member of the David Warshaw Laboratory

Research Description

My goal is to design, develop, fabricate and support world class microscopy systems for research in molecular physiology. Our research demands high sensitivity with fast temporal and precise spatial resolution. These systems include integrated Laser Optical Tweezers with dual color Total Internal Reflection Microscopy (TIRFM) along with single molecule detection, manipulation and tracking capabilities. Mechanical measurements of pico-newton force, nanometer displacement, and pico-newtons/ nanometer stiffness are used to address questions in single molecules. These techniques are applied to protein ensembles, intercellular dynamics, and molecular protein- protein interactions. High speed fluorescent imaging of single molecule dynamics are possible using state of the art ICCD cameras with TIR and far field illumination. Recent initiatives include high speed 3D tracking, STORM, and PALM Super Resolution microscopy. Myosin, Kinesin, C-Protein, Actin, Microtubules and other Cytoskeletal proteins are studied with our techniques.

Current Publications:

Mathew NR, Baumgartner F, Braun L, O’Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, Yan KL, Weber A, Tugues S, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, Bertz H, Wäsch R, Haag J, Schmidts A, Schultheiss M, Bettinger D, Thimme R, Ullrich E, Tanriver Y, Vuong GL, Arnold R, Hemmati P, Wolf D, Ditschkowski M, Jilg C, Wilhelm K, Leiber C, Gerull S, Halter J, Lengerke C, Pabst T, Schroeder T, Kobbe G, Rösler W, Doostkam S, Meckel S, Stabla K, Metzelder SK, Halbach S, Brummer T, Hu Z, Dengjel J, Hackanson B, Schmid C, Holtick U, Scheid C, Spyridonidis A, Stölzel F, Ordemann R, Müller LP, Sicre-de-Fontbrune F, Ihorst G, Kuball J, Ehlert JE, Feger D, Wagner EM, Cahn JY, Schnell J, Kuchenbauer F, Bunjes D, Chakraverty R, Richardson S, Gill S, Kröger N, Ayuk F, Vago L, Ciceri F, Müller AM, Kondo T, Teshima T, Klaeger S, Kuster B, Kim DDH, Weisdorf D, van der Velden W, Dörfel D, Bethge W, Hilgendorf I, Hochhaus A, Andrieux G, Börries M, Busch H, Magenau J, Reddy P, Labopin M, Antin JH, Henden AS, Hill GR, Kennedy GA, Bar M, Sarma A, McLornan D, Mufti G, Oran B, Rezvani K, Sha O, Negrin RS, Nagler A, Prinz M, Burchert A, Neubauer A, Beelen D, Mackensen A, von Bubnoff N, Herr W, Becher B, Socié G, Caligiuri MA, Ruggiero E, Bonini C, Häcker G, Duyster J, Finke J, Pearce E, Blazar BR, Zeiser R (2018) Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med : .

Scott A, Tey SK, Butler J, Kennedy GA (2018) “Diagnostic Utility of Endoscopy and Biopsy in Suspected Acute Gastrointestinal Graft Versus Host Disease (GI-GVHD) Following Haematopoietic Progenitor Cell Transplantation (HPCT).” Biol Blood Marrow Transplant : .

Kennedy GA, Wick MR, Keel PK (2018) Eating disorders in children: is avoidant-restrictive food intake disorder a feeding disorder or an eating disorder and what are the implications for treatment? F1000Res 7: 88.

Taylor E, Morris K, Ellis M, Marlton P, Baveshi K, Clarey J, Irving I, Cochrane T, Kennedy G (2018) FLT3-ITD positive acute myeloid leukemia: A retrospective analysis of the role of allogeneic transplant and allelic ratio in patient management. Asia Pac J Clin Oncol : .

Wijewickrema S, Zhou Y, Ioannou I, Copson B, Piromchai P, Yu C, Briggs R, Bailey J, Kennedy G, O’Leary S (2018) Presentation of automated procedural guidance in surgical simulation: results of two randomised controlled trials. J Laryngol Otol : 1-7.

Huseth AS, Chappell TM, Chitturi A, Jacobson AL, Kennedy GG (2018) Insecticide Resistance Signals Negative Consequences of Widespread Neonicotinoid Use on Multiple Field Crops in the U.S. Cotton Belt. Environ Sci Technol : .

Alvaro PK, Burnett NM, Kennedy GA, Min WYX, McMahon M, Barnes M, Jackson M, Howard ME (2018) Driver education: Enhancing knowledge of sleep, fatigue and risky behaviour to improve decision making in young drivers. Accid Anal Prev 112: 77-83.


All Kennedy publications