Guy Kennedy

Guy  Kennedy,

Research Engineer


HSRF 115

Lab Group

A member of the David Warshaw Laboratory

Research Description

My goal is to design, develop, fabricate and support world class microscopy systems for research in molecular physiology. Our research demands high sensitivity with fast temporal and precise spatial resolution. These systems include integrated Laser Optical Tweezers with dual color Total Internal Reflection Microscopy (TIRFM) along with single molecule detection, manipulation and tracking capabilities. Mechanical measurements of pico-newton force, nanometer displacement, and pico-newtons/ nanometer stiffness are used to address questions in single molecules. These techniques are applied to protein ensembles, intercellular dynamics, and molecular protein- protein interactions. High speed fluorescent imaging of single molecule dynamics are possible using state of the art ICCD cameras with TIR and far field illumination. Recent initiatives include high speed 3D tracking, STORM, and PALM Super Resolution microscopy. Myosin, Kinesin, C-Protein, Actin, Microtubules and other Cytoskeletal proteins are studied with our techniques.

Current Publications:

Kennedy GJ (2018) The Trifecta of Benefits in Depression Care for Patients With Advanced Chronic Obstructive Pulmonary Disease. Am J Geriatr Psychiatry : .

Yegin S, Saha BC, Kennedy GJ, Leathers TD (2019) Valorization of egg shell as a detoxifying and buffering agent for efficient polymalic acid production by Aureobasidium pullulans NRRL Y-2311-1 from barley straw hydrolysate. Bioresour Technol 278: 130-137.

Kennedy G, McGarry K, Bradley G, Harkin DW (2019) All-Cause Mortality Amongst Patients Undergoing Above and Below Knee Amputation in a Regional Vascular Centre within 2014-2015. Ulster Med J 88(1): 30-35.

Lee MH, Siddoway B, Kaeser GE, Segota I, Rivera R, Romanow WJ, Liu CS, Park C, Kennedy G, Long T, Chun J (2019) Publisher Correction: Somatic APP gene recombination in Alzheimer’s disease and normal neurons. Nature : .

Kennedy GA, Jean Forney K, Pinner D, Martinez KM, Buchman-Schmitt JM, Keel PK (2019) Reducing anticipated non-suicidal self-injury by improving body esteem in individuals with weight suppression: A proof of concept study. Int J Eat Disord : .

Kennedy G, Gallego B (2019) Clinical prediction rules: A systematic review of healthcare provider opinions and preferences. Int J Med Inform 123: 1-10.

Mathes BM, Kennedy GA, Wilver NL, Carlton CN, Cougle JR (2018) A multi-method analysis of incompleteness in behavioral treatment of contamination-based OCD. Behav Res Ther 114: 1-6.


All Kennedy publications