Guy Kennedy

Guy  Kennedy,

Research Engineer


HSRF 115

Lab Group

A member of the David Warshaw Laboratory

Research Description

My goal is to design, develop, fabricate and support world class microscopy systems for research in molecular physiology. Our research demands high sensitivity with fast temporal and precise spatial resolution. These systems include integrated Laser Optical Tweezers with dual color Total Internal Reflection Microscopy (TIRFM) along with single molecule detection, manipulation and tracking capabilities. Mechanical measurements of pico-newton force, nanometer displacement, and pico-newtons/ nanometer stiffness are used to address questions in single molecules. These techniques are applied to protein ensembles, intercellular dynamics, and molecular protein- protein interactions. High speed fluorescent imaging of single molecule dynamics are possible using state of the art ICCD cameras with TIR and far field illumination. Recent initiatives include high speed 3D tracking, STORM, and PALM Super Resolution microscopy. Myosin, Kinesin, C-Protein, Actin, Microtubules and other Cytoskeletal proteins are studied with our techniques.

Current Publications:

Sparks H, Kondo H, Hooper S, Munro I, Kennedy G, Dunsby C, French P, Sahai E (2018) Heterogeneity in tumor chromatin-doxorubicin binding revealed by in vivo fluorescence lifetime imaging confocal endomicroscopy. Nat Commun 9(1): 2662.

Kennedy GA, Klein KM, Keel PK (2018) Prevalence and predictors of parental concern for children’s weight from 2002 to 2012. Public Health 162: 58-62.

Saha BC, Kennedy GJ, Bowman MJ, Qureshi N, Dunn RO (2018) Factors Affecting Production of Itaconic Acid from Mixed Sugars by Aspergillus terreus. Appl Biochem Biotechnol : .

Oduor FO, Boedecker J, Kennedy G, Mituki-Mungiria D, Termote C (2018) Caregivers’ nutritional knowledge and attitudes mediate seasonal shifts in children’s diets. Matern Child Nutr : e12633.

Kennedy G, Lewis VA, Kundu S, Mousqu├ęs J, Colla CH (2018) Accountable Care Organizations and Post-Acute Care: A Focus on Preferred SNF Networks. Med Care Res Rev : 1077558718781117.

Awal DH, Jaffer M, Charan G, Ball RE, Kennedy G, Thomas S, Farook SA, Mills C, Ayliffe P (2018) Costochondral grafting for paediatric temporomandibular joint reconstruction: 10-year outcomes in 55 cases. Int J Oral Maxillofac Surg : .

Women’s Dietary Diversity Project (WDDP) Study Group . (2017) Development of a Dichotomous Indicator for Population-Level Assessment of Dietary Diversity in Women of Reproductive Age. Curr Dev Nutr 1(12): .


All Kennedy publications