Guy Kennedy


Guy  Kennedy,

Research Engineer


Contact

Office:
HSRF 115
802-656-9420


Lab Group

A member of the David Warshaw Laboratory

Research Description

My goal is to design, develop, fabricate and support world class microscopy systems for research in molecular physiology. Our research demands high sensitivity with fast temporal and precise spatial resolution. These systems include integrated Laser Optical Tweezers with dual color Total Internal Reflection Microscopy (TIRFM) along with single molecule detection, manipulation and tracking capabilities. Mechanical measurements of pico-newton force, nanometer displacement, and pico-newtons/ nanometer stiffness are used to address questions in single molecules. These techniques are applied to protein ensembles, intercellular dynamics, and molecular protein- protein interactions. High speed fluorescent imaging of single molecule dynamics are possible using state of the art ICCD cameras with TIR and far field illumination. Recent initiatives include high speed 3D tracking, STORM, and PALM Super Resolution microscopy. Myosin, Kinesin, C-Protein, Actin, Microtubules and other Cytoskeletal proteins are studied with our techniques.

Current Publications:

Kennedy G, Gallego B (2019) Clinical prediction rules: A systematic review of healthcare provider opinions and preferences. Int J Med Inform 123: 1-10.

Mathes BM, Kennedy GA, Wilver NL, Carlton CN, Cougle JR (2018) A multi-method analysis of incompleteness in behavioral treatment of contamination-based OCD. Behav Res Ther 114: 1-6.

Chappell TM, Huseth AS, Kennedy GG (2019) Stability of neonicotinoid sensitivity in Frankliniella fusca populations found in agroecosystems of the southeastern United States. Pest Manag Sci : .

Kennedy GM, Min MY, Fitzgerald JF, Nguyen MT, Schultz SL, Crum MT, Starke JA, Butkus MA, Bowman DD, Labare MP (2018) Inactivation of the bacterial pathogens Staphylococcus pseudintermedius and Acinetobacter baumannii by butanoic acid. J Appl Microbiol : .

D’Ambrosio DA, Huseth AS, Kennedy GG (2018) Determining Frankliniella fusca (Thysanoptera: Thripidae) Egg Distribution in Neonicotinoid Seed-Treated Cotton. J Econ Entomol : .

Shyamsundar M, O’Kane C, Perkins GD, Kennedy G, Campbell C, Agus A, Phair G, McAuley D (2018) Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial. Trials 19(1): 690.

Murunga P, Kennedy GM, Imboma T, Malaki P, Kariuki D, Ndiema E, Obanda V, Agwanda B, Lichoti JK, Ommeh SC (2018) Mitochondrial DNA D-Loop Diversity of the Helmeted Guinea Fowls in Kenya and Its Implications on HSP70 Gene Functional Polymorphism. Biomed Res Int 2018: 7314038.

 

All Kennedy publications