Guy Kennedy

Guy  Kennedy,

Research Engineer


HSRF 115

Lab Group

A member of the David Warshaw Laboratory

Research Description

My goal is to design, develop, fabricate and support world class microscopy systems for research in molecular physiology. Our research demands high sensitivity with fast temporal and precise spatial resolution. These systems include integrated Laser Optical Tweezers with dual color Total Internal Reflection Microscopy (TIRFM) along with single molecule detection, manipulation and tracking capabilities. Mechanical measurements of pico-newton force, nanometer displacement, and pico-newtons/ nanometer stiffness are used to address questions in single molecules. These techniques are applied to protein ensembles, intercellular dynamics, and molecular protein- protein interactions. High speed fluorescent imaging of single molecule dynamics are possible using state of the art ICCD cameras with TIR and far field illumination. Recent initiatives include high speed 3D tracking, STORM, and PALM Super Resolution microscopy. Myosin, Kinesin, C-Protein, Actin, Microtubules and other Cytoskeletal proteins are studied with our techniques.

Current Publications:

Feld SI, Tevis SE, Cobian AG, Craven MW, Kennedy GD (2016) Multiple postoperative complications: Making sense of the trajectories. Surgery : .

Scrima A, Lubner MG, King S, Kennedy G, Pickhardt PJ (2016) Abdominal Multidetector Computed Tomography for Suspected Small-Bowel Obstruction: Multireader Study Comparing Radiologist Performance for Predicting Surgical Outcomes. J Comput Assist Tomogr : .

Kennedy GJ (2016) Behavioral Interventions for Patients with Major Depression and Severe COPD. Am J Geriatr Psychiatry 24(11): 975-976.

Nakagaki M, Barras M, Curley C, Butler JP, Kennedy GA (2016) A randomized trial of olanzapine versus palonosetron versus infused ondansetron for the treatment of breakthrough chemotherapy-induced nausea and vomiting in patients undergoing hematopoietic stem cell transplantation. Support Care Cancer : .

Yue MC, Collins JT, Subramoniapillai E, Kennedy GA (2016) Successful use of oseltamivir prophylaxis in managing a nosocomial outbreak of influenza A in a hematology and allogeneic stem cell transplant unit. Asia Pac J Clin Oncol : .

Jacobson AL, Nault BA, Vargo EL, Kennedy GG (2016) Restricted Gene Flow among Lineages of Thrips tabaci Supports Genetic Divergence Among Cryptic Species Groups. PLoS One 11(9): e0163882.

Kennedy G, Hardman RJ, Macpherson H, Scholey AB, Pipingas A (2016) How Does Exercise Reduce the Rate of Age-Associated Cognitive Decline? A Review of Potential Mechanisms. J Alzheimers Dis : .


All Kennedy publications