Samantha Beck Previs

Samantha Beck Previs,

Research Technician


B.S. in Biology from Saint Michael’s College in 2000.


HSRF 115

HSRF 115

Lab Group

A member of the David Warshaw Laboratory

Research Description

I am involved in experiments looking at the function of myosin-binding protein C and its role in cardiac muscle contraction, insulin granule secretion, and myosin transport on actin networks. I also provide general laboratory support by preparing reagents and ordering needed supplies.


Highlighted Publications

Ali MY, Previs SB, Trybus KM, Sweeney HL, Warshaw DM. Myosin VI has a One Track Mind Versus Myosin Va When Moving on Actin Bundles or at an Intersection. Traffic. 2013 Jan;14(1):70-81

Weith AE, Previs MJ, Hoeprich GJ, Previs SB, Gulick J, Robbins J, Warshaw DM. The extent of cardiac myosin binding protein-C phosphorylation modulates actomyosin function in a graded manner. J Muscle Res Cell Motil. 2012 Dec;33(6):449-59.

Previs MJ, Beck Previs S, Gulick J, Robbins J, Warshaw DM. Molecular mechanics of cardiac myosin-binding protein C in native thick filaments. Science. 2012 Sep 7;337(6099):1215-8.

Debold EP, Beck SE, Warshaw DM. Effect of low pH on single skeletal muscle myosin mechanics and kinetics. Am J Physiol Cell Physiol. 2008 Jul;295(1):C173-9.

Debold EP, Schmitt JP, Patlak JB, Beck SE, Moore JR, Seidman JG, Seidman C, Warshaw DM. Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay. Am J Physiol Heart Circ Physiol. 2007