Andrew Lombardo
Graduate Student
Background
I received my B.S. in Biophysics from the State University of New York at Geneseo in 2011. In Fall 2011, I entered the graduate program in the Department of Mol. Physiology & Biophysics.
Contact
Office:
HSRF 115
802-656-3820
Lab:
HSRF 115
Lab Group
A member of the David Warshaw Laboratory
Research Description
Myosin V and VI are processive molecular motors which transport cargo along actin filaments in a hand-over-hand fashion. Movement of these motors on differing actin tracks has been an area of intense study as post translational modifications, myosin associating proteins, bundles of actin and branching actin have all been shown to alter the way in which myosin navigates its path. As a part of the larger goal of the Warshaw laboratory, I am looking to increase complexity in our in vitro experiments to more accurately portray the environment in which myosin moves within the living cell.
Highlighted Publications
Wang Y, Tanner BC, Lombardo AT, Tremble SM, Maughan DW, Vanburen P, Lewinter MM, Robbins J, Palmer BM. Cardiac myosin isoforms exhibit differential rates of MgADP release and MgATP binding detected by myocardial viscoelasticity. J Mol Cell Cardiol. 2012. [Epub ahead of print]
Freeman CG, Fiksel G, Stoeckl C, Sinenian N, Canfield MJ, Graeper GB, Lombardo AT, Stillman CR, Padalino SJ, Mileham C, Sangster TC, Frenje JA. Calibration of a Thomson parabola ion spectrometer and Fujifilm imaging plate detectors for protons, deuterons, and alpha particles. Rev Sci Instrum. 2011 Jul;82(7):073301.