Research Description

Myosin V and VI are processive molecular motors which transport cargo along actin filaments in a hand-over-hand fashion. Movement of these motors on differing actin tracks has been an area of intense study as post translational modifications, myosin associating proteins, bundles of actin and branching actin have all been shown to alter the way in which myosin navigates its path. As a part of the larger goal of the Warshaw laboratory, I am looking to increase complexity in our in vitro experiments to more accurately portray the environment in which myosin moves within the living cell.