{"id":815,"date":"2021-09-10T07:00:00","date_gmt":"2021-09-10T11:00:00","guid":{"rendered":"http:\/\/physioweb.uvm.edu\/stumpff-lab\/?p=815"},"modified":"2022-02-10T10:43:31","modified_gmt":"2022-02-10T15:43:31","slug":"new-preprint-describing-alex-thompsons-investigation-of-pathogenic-mutations-in-kif22-now-available","status":"publish","type":"post","link":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/2021\/09\/10\/new-preprint-describing-alex-thompsons-investigation-of-pathogenic-mutations-in-kif22-now-available\/","title":{"rendered":"New preprint describing Alex Thompson&#8217;s investigation of pathogenic mutations in KIF22 now available"},"content":{"rendered":"\n<p>This work describes how point mutations in KIF22 that dominantly cause a rare bone development disorder prevent inactivation of KIF22&#8217;s activity at the metaphase-to-anaphase transition. Check out the preprint <a rel=\"noreferrer noopener\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.09.29.462402v2\" data-type=\"URL\" data-id=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.09.29.462402v2\" target=\"_blank\">here<\/a>. Also see Alex&#8217;s Tweetorial describing the paper <a href=\"https:\/\/twitter.com\/alexfthompson\/status\/1445026496704307205\" data-type=\"URL\" data-id=\"https:\/\/twitter.com\/alexfthompson\/status\/1445026496704307205\" target=\"_blank\" rel=\"noreferrer noopener\">here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This work describes how point mutations in KIF22 that dominantly cause a rare bone development disorder prevent inactivation of KIF22&#8217;s activity at the metaphase-to-anaphase transition. Check out the preprint here. Also see Alex&#8217;s Tweetorial describing the paper here.<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/posts\/815"}],"collection":[{"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/comments?post=815"}],"version-history":[{"count":1,"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/posts\/815\/revisions"}],"predecessor-version":[{"id":816,"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/posts\/815\/revisions\/816"}],"wp:attachment":[{"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/media?parent=815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/categories?post=815"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/physioweb.uvm.edu\/stumpff-lab\/wp-json\/wp\/v2\/tags?post=815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}