{"id":120,"date":"2012-12-03T10:15:05","date_gmt":"2012-12-03T14:15:05","guid":{"rendered":"http:\/\/blog.uvm.edu\/dwarshaw\/?page_id=120"},"modified":"2017-08-09T18:52:27","modified_gmt":"2017-08-09T18:52:27","slug":"single-molecule-biophysical-techniques","status":"publish","type":"page","link":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/single-molecule-biophysical-techniques\/","title":{"rendered":"Single Molecule Biophysical Techniques"},"content":{"rendered":"<table style=\"width: 900px;\" border=\"0\">\n<tbody>\n<tr>\n<td width=\"30%\"><div id='Research_Interests' class='widgets_on_page wop_tiny1  wop_small1  wop_medium1  wop_large1  wop_wide1'>\n\t\t\t<ul><li id=\"nav_menu-9\" class=\"widget widget_nav_menu\"><div class=\"menu-research-interests-container\"><ul id=\"menu-research-interests\" class=\"menu\"><li id=\"menu-item-407\" class=\"menu-item menu-item-type-custom menu-item-object-custom menu-item-407\"><a href=\"http:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/\">Myosin: A Molecular Motor<\/a><\/li>\n<li id=\"menu-item-403\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-403\"><a href=\"https:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/myosin-binding-protein-c-mybp-c\/\">Myosin Binding Protein-C (MyBP-C)<\/a><\/li>\n<li id=\"menu-item-404\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-404\"><a href=\"https:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/single-molecule-biophysical-techniques\/\">Single Molecule <br>Biophysical Techniques<\/a><\/li>\n<li id=\"menu-item-400\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-400\"><a href=\"https:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/intracellular-cargo-transport\/\">Intracellular Cargo Transport<\/a><\/li>\n<li id=\"menu-item-399\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-399\"><a href=\"https:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/heart-disease-associated-with-cmybp-c-mutations\/\">Heart and Skeletal Muscle Diseases Associated with cMyBP-C Mutations<\/a><\/li>\n<li id=\"menu-item-405\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-405\"><a href=\"https:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/thin-filament-regulation\/\">Thin Filament Activation by cMyBP-C<\/a><\/li>\n<\/ul><\/div><\/li><\/ul><\/div><!-- widgets_on_page --><\/td>\n<td>\n<h4>RESEARCH INTERESTS<\/h4>\n<h1>Single Molecule Biophysical Techniques<\/h1>\n<p>To characterize the molecular structure and function of the actomyosin motor and its interaction with modulatory proteins such as myosin binding protein-C, we have developed an array of single molecule biophysical techniques that can measure the force and motion of a single molecular motor or any protein-protein interaction. Examples of these techniques are the laser trap and super-resolution fluorescence microscopy. <a title=\"Techniques\" href=\"http:\/\/physioweb.uvm.edu\/warshaw-lab\/techniques\/\" target=\"_blank\" rel=\"noopener noreferrer\">Novel biophysical techniques<\/a> are combined to address interesting research problems ranging from heart disease to the ability of myosin motors to navigate the complex cytoskeleton within cells during cargo transport.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>RESEARCH INTERESTS Single Molecule Biophysical Techniques To characterize the molecular structure and function of the actomyosin motor and its interaction with modulatory proteins such as myosin binding protein-C, we have developed an array of single molecule biophysical techniques that can &hellip; <a href=\"https:\/\/physioweb.uvm.edu\/warshaw-lab\/research-interests\/single-molecule-biophysical-techniques\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":13,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"sidebar-page.php","meta":[],"_links":{"self":[{"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/pages\/120"}],"collection":[{"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/comments?post=120"}],"version-history":[{"count":11,"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/pages\/120\/revisions"}],"predecessor-version":[{"id":781,"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/pages\/120\/revisions\/781"}],"up":[{"embeddable":true,"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/pages\/13"}],"wp:attachment":[{"href":"https:\/\/physioweb.uvm.edu\/warshaw-lab\/wp-json\/wp\/v2\/media?parent=120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}