Publications

PREPRINTS

Malaby HLH, Lessard DV, Berger CL, and Stumpff J. (2018). Human kinesin Kif18A’s neck linker permits navigation of microtubule bound obstacles within the mitotic spindle. bioRxiv doi: https://doi.org/10.1101/364380 (final version published in Life Science Alliance Jan 17th, 2019)

 

Fonseca CL, Malaby HLH, Sepaniac LA, Martin W, Byers C, Czechanski A, Messinger D, Tang ME, Ohi R, Reinholdt LG, and Stumpff J. (2018). Mitotic chromosome alignment is required for proper nuclear envelope reassembly. bioRxiv doi: https://doi.org/10.1101/343475, highlighted by preLights (final version published in JCB Feb 7th, 2019)

 

Malaby H, Dumas M, Ohi R, and Stumpff J. (2018). Kinesin binding protein (KBP) buffers the activity of Kif18A and Kif15 in mitosis to ensure accurate chromosome segregation. bioRxiv doi: https://doi.org/10.1101/343046. (final version published in JCB Feb 1st, 2019)

 

Kim H and Stumpff J. (2018). Kif18A promotes Hec1 dephosphorylation to coordinate chromosome alignment with kinetochore microtubule attachment. bioRxiv doi: https://doi.org/10.1101/304147.

SELECTED PUBLICATIONS

Fonseca CL, Malaby HLH, Sepaniac LA, Martin W, Byers C, Czechanski A, Messinger D, Tang ME, Ohi R, Reinholdt LG, and Stumpff J. Mitotic chromosome alignment ensures mitotic fidelity by promoting interchromosomal compaction during anaphaseJCB. 2019, epub, PMID: 30733233

 

Malaby H, Dumas M, Ohi R, and Stumpff J. Kinesin binding protein ensures accurate chromosome segregation by buffering Kif18A and Kif15. JCB. 2019, epub, PMID: 30709852

 

Malaby HLH, Lessard DV, Berger CL, and Stumpff J.  KIF18A’s neck linker permits navigation of microtubule-bound obstacles within the mitotic spindleLSA. 2019, 2:e201800169. PMID: 30655363

 

Muretta JM, Reddy BJN, Scarabelli G, Thompson AF, Jariwala S, Major J, Venere M, Rich JN, Willard B, Thomas DD, Stumpff J, Grant BJ, Gross SP, Rosenfeld SS. A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function. PNAS. 2018, 115: E1779-E1788. PMID: 29432173.

 

Tracy KM, Tye CE, Ghule PN, Malaby HLH, Stumpff J, Stein LJ, Stein GS, Lian JB. Mitotically-associated lncRNA (MANCR) affects genomic stability and cell division in aggressive breast cancer. Mol Cancer Res. 2018. PMID: 29378907.

 

Zhou J, Chan J, Lambelé M, Yusufzai T, Stumpff J, Opresko PL, Thali M, Wallace SS. NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis. Cell Reports. 2017, 20: 2044-2056. PMID: 28854357.

 

Fonseca C and Stumpff J. Quantification of mitotic chromosome alignment. Methods Mol Biol. 2016, 1413: 253-62. PMID: 27193854. PDF_Fonseca_2016

 

Czechanski A, Kim H, Byers C, Greenstein I, Stumpff J*, Reinholdt LG*. Kif18a Is specifically required for mitotic progression during germ line development. Dev Biol. 2015 June 15, 402(2):253-62 .PMID:25824710. (*corresponding authors) PDF_Czechanski_2015

 

Malaby, HLH and Stumpff, J. Microtubule recognition: A curvy attraction. Curr Biol. 2014 Oct 24 (20): R998-R1000. PDF_Malaby_2014

 

Kim H, Fonseca C and Stumpff J. A unique kinesin-8 surface loop provides specificity for chromosome alignmentMol Biol Cell. 2014 Nov 25 (21): 3319-3329.  PMID: 25208566. PDF_Kim_2014

 

Stumpff J, Ghule PN, Shimamura A, Stein JL, Greenblatt M. Spindle microtubule dysfunction and cancer predispositionJ Cell Physiol. 2014 Dec, 229 (12): 1881-3. doi: 10.1002/jcp.24691. PMID: 24905602 PDF_Stumpff_2014_JCP

 

Bissonette S, Stumpff J. Quantifying Mitotic Chromosome Dynamics and Positioning.Journal of Cellular Physiology: Volume 229, Number 10, October 2  J Cell Physiol. 2014 Oct 229(10):1301-05. doi: 10.1002/jcp.24634. PMID: 24683081 PDF_Bissonette_2014

(Featured on journal Cover)

 

Cunniff B, Snider GW, Fredette N, Stumpff J, Hondal RJ, Heintz NH. Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine. Redox Biol. 2014 Feb 19;2:475-84. doi: 10.1016/j.redox.2014.01.021. PMID: 24624337 PDF_Cunniff_2014

 

Cunniff B, Benson K, Stumpff J, Newick K, Held P, Taatjes D, Joseph J, Kalyanaraman B, Heintz NH. Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells.  J Cell Physiol. 2013 Apr;228(4):835-45. doi: 10.1002/jcp.24232. PMID: 23018647 PDF_Cunniff_2013

(Featured on journal Cover)

 

Stumpff J. Measuring microtubule thickness: an exercise in cooperativity.  Dev Cell. 2012 Jul 17;23(1):1-2. doi: 10.1016/j.devcel.2012.06.010. PMID: 22814594Cover of Developmental Cell, May 2012 PDF_Stumpff_2012_DC2

 

Stumpff J**, Wagenbach M, Franck A, Asbury CL, Wordeman L** Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension. Dev Cell. 2012 May 15;22(5):1017-29. doi: 10.1016/j.devcel.2012.02.013. PMID: 22595673 PDF_Stumpff_2012_DC1

(** co-corresponding authors) (Featured on journal Cover) (Cited on F1000 Prime)

 

Stumpff J**, Du Y**, English CA, Maliga Z, Wagenbach M, Asbury CL, Wordeman L, Ohi R. A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A.  Mol Cell. 2011 Sep 2;43(5):764-75. doi: 10.1016/j.molcel.2011.07.022. PMID: 21884977 PDF_Stumpff_2011

(** authors contributed equally) (Cited on F1000 Prime)

 

Mattison CP, Stumpff J, Wordeman L, Winey M. Mip1 associates with both the Mps1 kinase and actin, and is required for cell cortex stability and anaphase spindle positioning.  Cell Cycle. 2011 Mar 1;10(5):783-93. Epub 2011 Mar 1. PMID: 21325884 PDF_Mattison_2011

(Featured on journal Cover)

 

Wordeman L, Stumpff J. Microtubule length control, a team sport? Dev Cell. 2009 Oct;17(4):437-8. doi: 10.1016/j.devcel.2009.10.002. PMID: 9853556 PDF_Wordeman_2009

 

Garcia K, Stumpff J, Duncan T, Su TT. Tyrosines in the kinesin-5 head domain are necessary for phosphorylation by Wee1 and for mitotic spindle integrity.  Curr Biol. 2009 Oct 13;19(19):1670-6. doi: 10.1016/j.cub.2009.08.013. Epub 2009 Oct 1. PMID: 19800237 PDF_Garcia_2009

 

Stumpff J, von Dassow G, Wagenbach M, Asbury C, Wordeman L. The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment. Dev Cell. 2008 Feb;14(2):252-62. doi: 10.1016/j.devcel.2007.11.014. PMID: 18267093 PDF_Stumpff_2008_DevCell

(Cited on F1000 Prime)

 

Stumpff J, Asbury CL. Chromosome bi-orientation: Euclidian euploidy.  Curr Biol. 2008 Jan 22;18(2):R81-3. doi: 10.1016/j.cub.2007.11.036. PMID: 18211848 PDF_Stumpff_2008_CurrBiol

 

Stumpff J, Cooper J, Domnitz S, Moore AT, Rankin KE, Wagenbach M, Wordeman L. In vitro and in vivo analysis of microtubule-destabilizing kinesins.  Methods Mol Biol. 2007 ;392:37-49. PMID: 17951709

 

Stumpff J, Wordeman L.  Chromosome congression: the kinesin-8-step path to alignment. Curr Biol. 2007 May 1;17(9):R326-8. Review. PMID: 17470346 PDF_Stumpff_2007

 

Stumpff J, Kellogg DR, Krohne KA, Su TT.  Drosophila Wee1 interacts with members of the gammaTURC and is required for proper mitotic-spindle morphogenesis and positioning. Curr Biol. 2005 Sep 6;15(17):1525-34. PMID: 16139207 PDF_Stumpff_2005

 

Stumpff J, Duncan T, Homola E, Campbell SD, Su TT. Drosophila Wee1 kinase regulates Cdk1 and mitotic entry during embryogenesis. Curr Biol. 2004 Dec 14;14(23):2143-8. PMID: 15589158 PDF_Stumpff_2004

(Cited on F1000 Prime)

 

Su TT, Walker J, Stumpff J. Activating the DNA damage checkpoint in a developmental context.  Curr Biol. 2000 Feb 10;10(3):119-26. PMID: 10679321 PDF_Su_2000

 

Full list of Dr. Stumpff’s publications on Pubmed